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A novel regulatory element (E77) isolated from CHO‐K1 genomic DNA enhances stable gene expression in Chinese hamster ovary cells

Vectors flanked by regulatory DNA elements have been used to generate stable cell lines with high productivity and transgene stability; however, regulatory elements in Chinese hamster ovary (CHO) cells, which are the most widely used mammalian cells in biopharmaceutical production, are still poorly...

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Bibliografiska uppgifter
I publikationen:Biotechnol J
Huvudupphovsmän: Kang, Shin‐Young, Kim, Yeon‐Gu, Kang, Seunghee, Lee, Hong Weon, Lee, Eun Gyo
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY‐VCH Verlag 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067685/
https://ncbi.nlm.nih.gov/pubmed/26762773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201500464
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