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New cell line development for antibody-producing Chinese hamster ovary cells using split green fluorescent protein

BACKGROUND: The establishment of high producer is an important issue in Chinese hamster ovary (CHO) cell culture considering increased heterogeneity by the random integration of a transfected foreign gene and the altered position of the integrated gene. Fluorescence-activated cell sorting (FACS)-bas...

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Détails bibliographiques
Auteurs principaux: Kim, Yeon-Gu, Park, Byoungwoo, Ahn, Jung Oh, Jung, Joon-Ki, Lee, Hong Weon, Lee, Eun Gyo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428690/
https://ncbi.nlm.nih.gov/pubmed/22587529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-24
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