Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase

Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous GCR. Although effective, it is exceptionally expensive, and patients worldw...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Novo, Juliana Branco, Morganti, Ligia, Moro, Ana Maria, Paes Leme, Adriana Franco, Serrano, Solange Maria de Toledo, Raw, Isaias, Ho, Paulo Lee
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471063/
https://ncbi.nlm.nih.gov/pubmed/23091360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/875383
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