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Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase

Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous GCR. Although effective, it is exceptionally expensive, and patients worldw...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Novo, Juliana Branco, Morganti, Ligia, Moro, Ana Maria, Paes Leme, Adriana Franco, Serrano, Solange Maria de Toledo, Raw, Isaias, Ho, Paulo Lee
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471063/
https://ncbi.nlm.nih.gov/pubmed/23091360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/875383
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