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Generation of a Chinese Hamster Ovary Cell Line Producing Recombinant Human Glucocerebrosidase
Impaired activity of the lysosomal enzyme glucocerebrosidase (GCR) results in the inherited metabolic disorder known as Gaucher disease. Current treatment consists of enzyme replacement therapy by administration of exogenous GCR. Although effective, it is exceptionally expensive, and patients worldw...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471063/ https://ncbi.nlm.nih.gov/pubmed/23091360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/875383 |
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