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Design and Engineering of Deimmunized Biotherapeutics

Therapeutic proteins are powerful next-generation drugs able to effectively treat diverse and devastating diseases, but the development and use of biotherapeutics entails unique challenges and risks. In particular, protein drugs are subject to immune surveillance in the human body, and ensuing antid...

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Bibliografiske detaljer
Udgivet i:Curr Opin Struct Biol
Main Authors: Griswold, Karl E., Bailey-Kellogg, Chris
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067179/
https://ncbi.nlm.nih.gov/pubmed/27322891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.003
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