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Structure-Guided Deimmunization of Therapeutic Proteins

Therapeutic proteins continue to yield revolutionary new treatments for a growing spectrum of human disease, but the development of these powerful drugs requires solving a unique set of challenges. For instance, it is increasingly apparent that mitigating potential anti-therapeutic immune responses,...

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Détails bibliographiques
Auteurs principaux: Parker, Andrew S., Choi, Yoonjoo, Griswold, Karl E., Bailey-Kellogg, Chris
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576912/
https://ncbi.nlm.nih.gov/pubmed/23384000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0251
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