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Structure-based redesign of proteins for minimal T-cell epitope content

The protein universe displays a wealth of therapeutically relevant activities, but T cell driven immune responses to non-“self” biological agents present a major impediment to harnessing the full diversity of these molecular functions. Mutagenic T cell epitope deletion seeks to mitigate the immune r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Choi, Yoonjoo, Griswold, Karl E., Bailey-Kellogg, Chris
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763725/
https://ncbi.nlm.nih.gov/pubmed/23299435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.23213
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