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Design and Engineering of Deimmunized Biotherapeutics

Therapeutic proteins are powerful next-generation drugs able to effectively treat diverse and devastating diseases, but the development and use of biotherapeutics entails unique challenges and risks. In particular, protein drugs are subject to immune surveillance in the human body, and ensuing antid...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Griswold, Karl E., Bailey-Kellogg, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067179/
https://ncbi.nlm.nih.gov/pubmed/27322891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.003
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