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In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides.

The c-myb protooncogene encodes proteins that are critical for hematopoietic cell proliferation and development. Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth. Antisense oligodeoxynucleotides have been utilized for this purpo...

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Autors principals: Ratajczak, M Z, Kant, J A, Luger, S M, Hijiya, N, Zhang, J, Zon, G, Gewirtz, A M
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50649/
https://ncbi.nlm.nih.gov/pubmed/1281545
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