In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides.
The c-myb protooncogene encodes proteins that are critical for hematopoietic cell proliferation and development. Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth. Antisense oligodeoxynucleotides have been utilized for this purpo...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1992
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.11823 |
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