Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging.

The c-myb protooncogene is preferentially expressed in hematopoietic cells, and its encoded protein, Myb, is required for hematopoietic cell proliferation. To analyze the relative Myb dependence of normal and leukemic human hematopoietic progenitor cells, normal bone marrow cells, several types of l...

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Detalhes bibliográficos
Main Authors: Calabretta, B, Sims, R B, Valtieri, M, Caracciolo, D, Szczylik, C, Venturelli, D, Ratajczak, M, Beran, M, Gewirtz, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51229/
https://ncbi.nlm.nih.gov/pubmed/2006173
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