In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides.

The c-myb protooncogene encodes proteins that are critical for hematopoietic cell proliferation and development. Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth. Antisense oligodeoxynucleotides have been utilized for this purpo...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Ratajczak, M Z, Kant, J A, Luger, S M, Hijiya, N, Zhang, J, Zon, G, Gewirtz, A M
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.11823
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