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Allosteric Regulation of Mammalian Pantothenate Kinase
Pantothenate kinase is the master regulator of CoA biosynthesis and is feedback-inhibited by acetyl-CoA. Comparison of the human PANK3·acetyl-CoA complex to the structures of PANK3 in four catalytically relevant complexes, 5′-adenylyl-β,γ-imidodiphosphate (AMPPNP)·Mg(2+), AMPPNP·Mg(2+)·pantothenate,...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064008/ https://ncbi.nlm.nih.gov/pubmed/27555321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748061 |
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