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Compartmentalization of Mammalian Pantothenate Kinases

The pantothenate kinases (PanK) catalyze the first and the rate-limiting step in coenzyme A (CoA) biosynthesis and regulate the amount of CoA in tissues by differential isoform expression and allosteric interaction with metabolic ligands. The four human and mouse PanK proteins share a homologous car...

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Autori principali: Alfonso-Pecchio, Adolfo, Garcia, Matthew, Leonardi, Roberta, Jackowski, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496714/
https://ncbi.nlm.nih.gov/pubmed/23152917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049509
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