Rescuing cardiac automaticity in L‐type Cav1.3 channelopathies and beyond

Pacemaker activity of the sino‐atrial node generates the heart rate. Disease of the sinus node and impairment of atrioventricular conduction induce an excessively low ventricular rate (bradycardia), which cannot meet the needs of the organism. Bradycardia accounts for about half of the total workloa...

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Veröffentlicht in:J Physiol
Hauptverfasser: Mesirca, Pietro, Bidaud, Isabelle, Mangoni, Matteo E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Symposium section reviews: Voltage‐gated calcium channels ‐ from basic mechanisms to disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063940/
https://ncbi.nlm.nih.gov/pubmed/27374078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270678
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