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Monocrotaline-induced Pulmonary Hypertension Involves Downregulation of Anti-aging Protein Klotho and eNOS activity
The objective of this study is to investigate whether stem cell delivery of secreted Klotho (SKL), an aging-suppressor protein, attenuates monocrotaline (MCT)-induced pulmonary vascular dysfunction and remodelling. Overexpression of SKL in mesenchymal stem cells (MSCs) was achieved by transfecting M...
Gorde:
| Argitaratua izan da: | Hypertension |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063703/ https://ncbi.nlm.nih.gov/pubmed/27672025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08184 |
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