Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats

BACKGROUND: Mast cells (MCs) are implicated in inflammation and tissue remodeling. Accumulation of lung MCs is described in pulmonary hypertension (PH); however, whether MC degranulation and c-kit, a tyrosine kinase receptor critically involved in MC biology, contribute to the pathogenesis and progr...

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Detalhes bibliográficos
Main Authors: Dahal, Bhola K, Kosanovic, Djuro, Kaulen, Christina, Cornitescu, Teodora, Savai, Rajkumar, Hoffmann, Julia, Reiss, Irwin, Ghofrani, Hossein A, Weissmann, Norbert, Kuebler, Wolfgang M, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104382/
https://ncbi.nlm.nih.gov/pubmed/21535881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-60
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