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A Novel Insight into the Mechanism of Pulmonary Hypertension Involving Caveolin-1 Deficiency and eNOS Activation

Severe pulmonary hypertension (PH) is characterized by a progressive increase in pulmonary vascular resistance and vascular remodeling leading to right heart failure and early death. Our recent studies employing the novel mouse model with genetic deletions of caveolin-1 (Cav1) and eNOS (NOS3) have d...

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Detalhes bibliográficos
Main Authors: Zhao, You-Yang, Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855158/
https://ncbi.nlm.nih.gov/pubmed/20382348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2010.02.003
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