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A Novel Insight into the Mechanism of Pulmonary Hypertension Involving Caveolin-1 Deficiency and eNOS Activation
Severe pulmonary hypertension (PH) is characterized by a progressive increase in pulmonary vascular resistance and vascular remodeling leading to right heart failure and early death. Our recent studies employing the novel mouse model with genetic deletions of caveolin-1 (Cav1) and eNOS (NOS3) have d...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855158/ https://ncbi.nlm.nih.gov/pubmed/20382348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2010.02.003 |
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