Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines

The ubiquitin-proteasome and autophagy-lysosome pathways are two major self-digestive systems for cellular proteins. Ubiquitinated misfolded proteins are degraded mostly by proteasome. However, when ubiquitinated proteins accumulate beyond the capacity of proteasome clearance, they are transported t...

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Detalles Bibliográficos
Publicado en:Int J Oncol
Main Authors: Miyahara, Kana, Kazama, Hiromi, Kokuba, Hiroko, Komatsu, Seiichiro, Hirota, Ayako, Takemura, Jun, Hirasawa, Kazuhiro, Moriya, Shota, Abe, Akihisa, Hiramoto, Masaki, Ishikawa, Takashi, Miyazawa, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063435/
https://ncbi.nlm.nih.gov/pubmed/27601063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3673
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