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Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm
In mammals, DNA methylation is introduced by the DNMT1, DNMT3A and DNMT3B methyltransferases, which are all large multi-domain proteins containing a catalytic C-terminal domain and an N-terminal part with regulatory functions. Recently, two novel regulatory principles of DNMTs were uncovered. It was...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062992/ https://ncbi.nlm.nih.gov/pubmed/27521372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw723 |
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