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Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm

In mammals, DNA methylation is introduced by the DNMT1, DNMT3A and DNMT3B methyltransferases, which are all large multi-domain proteins containing a catalytic C-terminal domain and an N-terminal part with regulatory functions. Recently, two novel regulatory principles of DNMTs were uncovered. It was...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Jeltsch, Albert, Jurkowska, Renata Z.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062992/
https://ncbi.nlm.nih.gov/pubmed/27521372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw723
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