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Mammalian DNA methyltransferases: new discoveries and open questions

As part of the epigenetic network, DNA methylation is a major regulator of chromatin structure and function. In mammals, it mainly occurs at palindromic CpG sites, but asymmetric methylation at non-CpG sites is also observed. Three enzymes are involved in the generation and maintenance of DNA methyl...

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Detalles Bibliográficos
Publicado en:Biochem Soc Trans
Main Authors: Gowher, Humaira, Jeltsch, Albert
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581191/
https://ncbi.nlm.nih.gov/pubmed/30154093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170574
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