Role of DNA Methyltransferases in the Epigenome

DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generati...

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Detalhes bibliográficos
Main Authors: Jeltsch, Albert, Gowher, Humaira
Formato: Livro
Idioma:Inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2020
Assuntos:
QH301-705.5
Q1-390
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
DNMTs
n/a
histone modification
TBRS
DNA methyltransferases
autoinhibition
epigenetics
DNMT
cell identity
embryogenesis
dwarfism
DNMT3B
germ cells
HSAN1E
USP7
DNMT3A
DNA methyltransferase
gene expression
DNMT1
de novo DNA methylation
DNA methyltransferase structure
UHRF1
DNA methyltransferase mechanism
allosteric regulation
rare diseases
DNA Methylation
maintenance DNA methylation
DNA methylation
ADCA-DN
PCC/PGL
ubiquitination
TETs
DNA methyltransferase function
molecular epigenetics
DNA methyltransferase regulation
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/58578
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