iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy

Adipose-resident invariant natural killer T (iNKT) cells are key players in metabolic regulation. iNKT cells are innate lipid sensors, and their activation, using their prototypic ligand α-galactosylceramide (αGalCer), induces weight loss and restores glycemic control in obesity. Here, iNKT activati...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Metab
Autori principali: Lynch, Lydia, Hogan, Andrew E., Duquette, Danielle, Lester, Chantel, Banks, Alexander, LeClair, Katherine, Cohen, David E., Ghosh, Abhisek, Lu, Bing, Corrigan, Michelle, Stevanovic, Darko, Maratos-Flier, Eleftheria, Drucker, Daniel J., O’Shea, Donal, Brenner, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061124/
https://ncbi.nlm.nih.gov/pubmed/27593966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.08.003
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi