FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

Certain white adipose tissue (WAT) depots are readily able to convert to a “brown-like” state with prolonged cold exposure or exposure to β-adrenergic compounds. This process is characterized by the appearance of pockets of uncoupling protein 1 (UCP1)-positive, multilocular adipocytes and serves to...

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Detalhes bibliográficos
Main Authors: Fisher, ffolliott M., Kleiner, Sandra, Douris, Nicholas, Fox, Elliott C., Mepani, Rina J., Verdeguer, Francisco, Wu, Jun, Kharitonenkov, Alexei, Flier, Jeffrey S., Maratos-Flier, Eleftheria, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278894/
https://ncbi.nlm.nih.gov/pubmed/22302939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.177857.111
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