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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
OBJECTIVE: Fibroblast growth factor 21 (FGF21) is a key mediator of fatty acid oxidation and lipid metabolism. Pharmacological doses of FGF21 improve glucose tolerance, lower serum free fatty acids, and lead to weight loss in obese mice. Surprisingly, however, FGF21 levels are elevated in obese ob/o...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Diabetes Association
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963536/ https://ncbi.nlm.nih.gov/pubmed/20682689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0193 |
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