Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

OBJECTIVE: Fibroblast growth factor 21 (FGF21) is a key mediator of fatty acid oxidation and lipid metabolism. Pharmacological doses of FGF21 improve glucose tolerance, lower serum free fatty acids, and lead to weight loss in obese mice. Surprisingly, however, FGF21 levels are elevated in obese ob/o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fisher, ffolliott M., Chui, Patricia C., Antonellis, Patrick J., Bina, Holly A., Kharitonenkov, Alexei, Flier, Jeffrey S., Maratos-Flier, Eleftheria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2010
Pynciau:
Metabolism
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963536/
https://ncbi.nlm.nih.gov/pubmed/20682689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0193
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg