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Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
OBJECTIVE: Fibroblast growth factor 21 (FGF21) is a key mediator of fatty acid oxidation and lipid metabolism. Pharmacological doses of FGF21 improve glucose tolerance, lower serum free fatty acids, and lead to weight loss in obese mice. Surprisingly, however, FGF21 levels are elevated in obese ob/o...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Diabetes Association
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963536/ https://ncbi.nlm.nih.gov/pubmed/20682689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0193 |
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