Fibroblast GroWTh Factor 21 and Thyroid Hormone Show Mutual Regulatory Dependency but Have Independent Actions In Vivo

Thyroid hormone (TH) regulates fibroblast growth factor 21 (FGF21) levels in the liver and in the adipose tissue. In contrast, peripheral FGF21 administration leads to decreased circulating levels of TH. These data suggest that FGF21 and TH could interact to regulate metabolism. In the present study...

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Main Authors: Domouzoglou, Eleni M., Fisher, ffolliott Martin, Astapova, Inna, Fox, Elliott C., Kharitonenkov, Alexei, Flier, Jeffrey S., Hollenberg, Anthony N., Maratos-Flier, Eleftheria
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Thyroid-TRH-TSH
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990851/
https://ncbi.nlm.nih.gov/pubmed/24564398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1902
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