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Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has provided unprecedented results in cancer treatment in the recent years. Development of chemical inhibitors for this pathway lags the antibody development because of insufficient structural information. The first nonpeptid...
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| Published in: | Oncotarget |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5058683/ https://ncbi.nlm.nih.gov/pubmed/27083005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8730 |
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