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Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1
Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has recently provided breakthrough progress in the treatment of melanoma, non-small cell lung cancer, and other types of cancer. Small-molecule drugs interfering with this pathway are highly awaited, but their development is...
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| Publicado no: | Structure |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752817/ https://ncbi.nlm.nih.gov/pubmed/26602187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.09.010 |
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