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Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1

Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has recently provided breakthrough progress in the treatment of melanoma, non-small cell lung cancer, and other types of cancer. Small-molecule drugs interfering with this pathway are highly awaited, but their development is...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Structure
Asıl Yazarlar: Zak, Krzysztof M., Kitel, Radoslaw, Przetocka, Sara, Golik, Przemyslaw, Guzik, Katarzyna, Musielak, Bogdan, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752817/
https://ncbi.nlm.nih.gov/pubmed/26602187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.09.010
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