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Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)
Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has provided unprecedented results in cancer treatment in the recent years. Development of chemical inhibitors for this pathway lags the antibody development because of insufficient structural information. The first nonpeptid...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5058683/ https://ncbi.nlm.nih.gov/pubmed/27083005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8730 |
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