Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Iaboni, Margherita, Fontanella, Raffaela, Rienzo, Anna, Capuozzo, Maria, Nuzzo, Silvia, Santamaria, Gianluca, Catuogno, Silvia, Condorelli, Gerolama, de Franciscis, Vittorio, Esposito, Carla Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://ncbi.nlm.nih.gov/pubmed/27648925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.73
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