Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Iaboni, Margherita, Fontanella, Raffaela, Rienzo, Anna, Capuozzo, Maria, Nuzzo, Silvia, Santamaria, Gianluca, Catuogno, Silvia, Condorelli, Gerolama, de Franciscis, Vittorio, Esposito, Carla Lucia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://ncbi.nlm.nih.gov/pubmed/27648925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.73
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