Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

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Detalles Bibliográficos
Publicado en:Mol Ther Nucleic Acids
Autores principales: Iaboni, Margherita, Fontanella, Raffaela, Rienzo, Anna, Capuozzo, Maria, Nuzzo, Silvia, Santamaria, Gianluca, Catuogno, Silvia, Condorelli, Gerolama, de Franciscis, Vittorio, Esposito, Carla Lucia
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://ncbi.nlm.nih.gov/pubmed/27648925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.73
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