Inhibition of Receptor Signaling and of Glioblastoma-derived Tumor Growth by a Novel PDGFRβ Aptamer

Platelet-derived growth factor receptor β (PDGFRβ) is a cell-surface tyrosine kinase receptor implicated in several cellular processes including proliferation, migration, and angiogenesis. It represents a compelling therapeutic target in many human tumors, including glioma. A number of tyrosine kina...

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Autori principali: Camorani, Simona, Esposito, Carla L, Rienzo, Anna, Catuogno, Silvia, Iaboni, Margherita, Condorelli, Gerolama, de Franciscis, Vittorio, Cerchia, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982505/
https://ncbi.nlm.nih.gov/pubmed/24566984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.300
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