An anti-PDGFRβ aptamer for selective delivery of small therapeutic peptide to cardiac cells

Small therapeutic peptides represent a promising field for the treatment of pathologies such as cardiac diseases. However, the lack of proper target-selective carriers hampers their translation towards a potential clinical application. Aptamers are cell-specific carriers that bind with high affinity...

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Bibliographic Details
Published in:PLoS One
Main Authors: Romanelli, Alessandra, Affinito, Alessandra, Avitabile, Concetta, Catuogno, Silvia, Ceriotti, Paola, Iaboni, Margherita, Modica, Jessica, Condorelli, Geroloma, Catalucci, Daniele
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841773/
https://ncbi.nlm.nih.gov/pubmed/29513717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193392
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