Targeting Insulin Receptor with a Novel Internalizing Aptamer

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Iaboni, Margherita, Fontanella, Raffaela, Rienzo, Anna, Capuozzo, Maria, Nuzzo, Silvia, Santamaria, Gianluca, Catuogno, Silvia, Condorelli, Gerolama, de Franciscis, Vittorio, Esposito, Carla Lucia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056995/
https://ncbi.nlm.nih.gov/pubmed/27648925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.73
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