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The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains
LDL Receptor-related Protein-1 (LRP1) is an endocytic receptor for diverse ligands. In neurons and neuron-like cells, ligand-binding to LRP1 initiates cell-signaling. Herein, we show that in PC12 and N2a neuron-like cells, LRP1 distributes into lipid rafts and non-raft plasma membrane fractions. Whe...
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Опубликовано в: : | Mol Cell Neurosci |
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Главные авторы: | , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056852/ https://ncbi.nlm.nih.gov/pubmed/27565578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.08.006 |
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