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LRP1 Assembles Unique Co-receptor Systems to Initiate Cell Signaling in Response to Tissue-type Plasminogen Activator and Myelin-associated Glycoprotein

In addition to functioning as an activator of fibrinolysis, tissue-type plasminogen activator (tPA) interacts with neurons and regulates multiple aspects of neuronal cell physiology. In this study, we examined the mechanism by which tPA initiates cell signaling in PC12 and N2a neuron-like cells. We...

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Detalhes bibliográficos
Main Authors: Mantuano, Elisabetta, Lam, Michael S., Gonias, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837140/
https://ncbi.nlm.nih.gov/pubmed/24129569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.509133
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