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Characterization of WY 14,643 and its Complex with Aldose Reductase
The peroxisome proliferator, WY 14,643 exhibits a pure non-competitive inhibition pattern in the aldehyde reduction and in alcohol oxidation activities of human Aldose reductase (hAR). Fluorescence emission measurements of the equilibrium dissociation constants, K(d), of oxidized (hAR•NADP(+)) and r...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056380/ https://ncbi.nlm.nih.gov/pubmed/27721416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34394 |
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