Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase

BACKGROUND: AMP-dependent protein kinase (AMPK) and peroxisome proliferator-activated receptor (PPAR) α facilitate fatty acid oxidation. We have shown that treatment of hepatoma cells with ethanol or feeding ethanol-containing diets to mice inhibited both PPARα and AMPK activity. Importantly, WY-14,...

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Hlavní autoři: Liangpunsakul, Suthat, Wou, Sung-Eun, Wineinger, Kevin D., Zeng, Yan, Cyganek, Izabela, Jayaram, Hiremagalur N., Crabb, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692688/
https://ncbi.nlm.nih.gov/pubmed/19236843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.02.006
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