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Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat.

Diethylnitrosamine (DEN), at a concentration of 100 parts/10(6) in drinking water for 14 days, caused the development, by 48 weeks, of very few liver tumours in 5 of 18 (27%) male F=344 rats fed control diet. When the DEN treatment was followed one week later by continuous feeding of the hypolipidem...

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Bibliografiske detaljer
Main Authors: Reddy, J. K., Rao, M. S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1978
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009753/
https://ncbi.nlm.nih.gov/pubmed/728341
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