טוען...
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor α to Wy-14,643-induced liver tumorigenesis
Peroxisome proliferators, such as lipid-lowering fibrate drugs, are agonists for the peroxisome proliferator-activated receptor α (PPARα). Sustained activation of PPARα leads to the development of liver tumors in rodents. Paradoxically, humans appear to be resistant to the induction of peroxisome pr...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447533/ https://ncbi.nlm.nih.gov/pubmed/16377806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgi329 |
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