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Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase
BACKGROUND: AMP-dependent protein kinase (AMPK) and peroxisome proliferator-activated receptor (PPAR) α facilitate fatty acid oxidation. We have shown that treatment of hepatoma cells with ethanol or feeding ethanol-containing diets to mice inhibited both PPARα and AMPK activity. Importantly, WY-14,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692688/ https://ncbi.nlm.nih.gov/pubmed/19236843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.02.006 |
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