MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease caused by loss of motor neurons. ALS patients experience rapid deterioration in muscle function with an average lifespan of 3–5 years after diagnosis. Currently, the most effective therapeutic only extends lifespan by a few months, t...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Glajch, Kelly E., Ferraiuolo, Laura, Mueller, Kaly A., Stopford, Matthew J., Prabhkar, Varsha, Gravanis, Achille, Shaw, Pamela J., Sadri-Vakili, Ghazaleh
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055348/
https://ncbi.nlm.nih.gov/pubmed/27716798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164103
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires