Cromolyn sodium delays disease onset and is neuroprotective in the SOD1(G93A) Mouse Model of amyotrophic lateral sclerosis

Accumulating evidence suggests that neuroinflammatory processes are implicated in the initiation and progression of amyotrophic lateral sclerosis (ALS). Previous reports have demonstrated an increase in microgliosis and astrogliosis in the lumbar spinal cord of SOD1(G93A) transgenic mice before the...

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Pubblicato in:Sci Rep
Autori principali: Granucci, Eric J., Griciuc, Ana, Mueller, Kaly A., Mills, Alexandra N., Le, Hoang, Dios, Amanda M., McGinty, Danielle, Pereira, Joao, Elmaleh, David, Berry, James D., Paganoni, Sabrina, Cudkowicz, Merit E., Tanzi, Rudolph E., Sadri-Vakili, Ghazaleh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881366/
https://ncbi.nlm.nih.gov/pubmed/31776380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53982-w
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