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A High-throughput and Pathophysiologically Relevant Astrocyte-motor Neuron Co-culture Assay for Amyotrophic Lateral Sclerosis Therapeutic Discovery

Amyotrophic lateral sclerosis (ALS) is an adult onset neurological disorder characterized by loss of motor neurons leading to progressive muscle wasting and eventually death. Astrocytes play a key role in disease pathogenesis. However, the ability to study astrocytic support towards motor neurons in...

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Vydáno v:Bio Protoc
Hlavní autoři: Stopford, Matthew J., Allen, Scott P., Ferraiuolo, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: Bio-Protocol 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774773/
https://ncbi.nlm.nih.gov/pubmed/31579294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3353
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