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Connexin 43 in Astrocytes Contributes to Motor Neuron Toxicity in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor neurons in the CNS. Astrocytes play a critical role in disease progression of ALS. Astrocytes are interconnected through a family of gap junction proteins known as connexins (Cx). Cx43 is a...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Almad, Akshata A., Doreswamy, Arpitha, Gross, Sarah K., Richard, Jean-Philippe, Huo, Yuqing, Haughey, Norman, Maragakis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635605/
https://ncbi.nlm.nih.gov/pubmed/27083773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22989
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