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Synthesis and evaluation of phenylalanine-derived trifluoromethyl ketones for peptide-based oxidation catalysis
We report the synthesis of phenylalanine-derived trifluoromethyl ketones for the in situ generation of dioxiranes for the purpose of oxidation catalysis. The key features of this synthesis include the use of a masked ketone strategy and a Negishi cross -coupling to access the parent amino acid. The...
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| 出版年: | Bioorg Med Chem |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053897/ https://ncbi.nlm.nih.gov/pubmed/27452284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.07.012 |
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