Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

The MDM2 promoter region contains several polymorphisms, some of which have been associated with MDM2 expression, cancer risk and age at cancer onset. del1518 (rs3730485) is an indel polymorphism residing in the MDM2 promoter P1 and is in almost complete linkage disequilibrium with the MDM2 promoter...

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Pubblicato in:Oncotarget
Autori principali: Gansmo, Liv B., Vatten, Lars, Romundstad, Pål, Hveem, Kristian, Ryan, Bríd M., Harris, Curtis C., Knappskog, Stian, Lønning, Per E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053751/
https://ncbi.nlm.nih.gov/pubmed/27081698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8705
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