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BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth
Multiple myeloma (MM) is a heterogeneous plasma cell malignancy and remains incurable. B-cell lymphoma-2 (BCL2) protein correlates with the survival and the drug resistance of myeloma cells. BH3 mimetics have been developed to disrupt the binding between BCL2 and its pro-apoptotic BCL2 family partne...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053685/ https://ncbi.nlm.nih.gov/pubmed/27049723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8513 |
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